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During perimenopause, the menstrual cycle and the periods become irregular and eventually stop altogether, but even when periods are still regular, the egg quality of women in their forties is lower than in younger women, making the likelihood of conceiving a healthy baby also reduced, particularly after age 42.
Men also experience a decline in fertility as they age, for example, the average time to pregnancy if a man is under 25 is just over 4.5 months but nearly two years if a man is over 40 (if the woman is under 25).
Irina had an accident at the age of 25 and was told by the doctors that she was unable to have children.
Later she married, and after many years of marriage eventually became pregnant and gave birth to her only son at the age of 51 in 1988.
The girl weighed 8.69 lb (3.94 kg) and did not breath on her own.